Is there a U-shaped curve of A1c versus mortality?

Alcohol and mortality: a U-shaped curve.

In a longitudinal study of civil servants, 1422 men were classified according to their average daily alcohol intake. Over 10 years of follow-up, the mortality rate was lower in men reporting moderate alcohol intake than in either non-drinkers or heavier drinkers (greater than 34 g alcohol per day). Cardiovascular mortality was greater in non-drinkers and non-cardiovascular mortality was greater...

Is there a U-shaped Relation between Competition and Investment?

We argue that, in a simple setting, the relation between the intensity of competition and cost-reducing investment is U-shaped. We consider a two-stage game with cost-reducing investments followed by a linear differentiated Cournot duopoly. We first show that, except for firms that are much less efficient than the competitor, investment in the subgame-perfect equilibrium is minimal for intermed...

Alcohol volume, drinking pattern, and cardiovascular disease morbidity and mortality: is there a U-shaped function?

The health effects of a binge pattern of alcohol consumption have not been widely investigated. The objective of this study was to evaluate the cardiovascular consequences of binge drinking (consumption of eight or more drinks at one sitting) and usual (nonbinge) drinking in a longitudinal, population-based study. Data obtained from 1,154 men and women aged 18-64 years interviewed in Winnipeg, ...

Is the J-shaped curve related to vascular mortality?

The two halves of U-shaped mortality

Gerontology focuses on deterioration with increasing age, but in most populations most variables, including survival probability, improve at early ages (ontogenescence) before deteriorating at advanced ages (senescence). The extent to which gerontology needs to consider this U-shaped pattern of risk over age depends upon the mechanistic, demographic and evolutionary links and interactions betwe...